2-Fluorodeschloroketamine or 2-FDCK is a relatively less known substance of the arylcyclohexylamine class which is known to produce anesthetic, dissociative and hallucinogenic effects when used. 2-FDCK is related structurally to other arylcyclohexylamines like ketamine and deschloroketamine and produces similar effects as well. It is popular among recreational users for its hallucinogenic effect inducing ability which has been described as an “out of body” experience in a state called dissociative anesthesia. It has a very brief documented history of human use and thus only little is known about its metabolism or toxicity.
2-FDCK is an arylcyclohexylamine drug and they are named after their structures which have a cyclohexane ring bound to the aromatic ring with an amine group. It is named for containing a fluorine molecule at its phenyl ring rather than chlorine which is there in ketamine. It is thought to produce all its effects due to its action as an NMDA receptor antagonist which means that it does not allow the electrical signals to pass between neurons in the brain and spinal cord. This produces an effect that leads to loss of feeling and difficulty moving.
